Understanding Oncogene Signaling and
We seek to understand how oncogenes reprogram cancer cells to drive cancer heterogeneity and metastasis.
We seek to understand the emergent properties of complex collections of tumor cells that self-assemble to cause therapy resistance and metastasis.
We seek to understand new cancer vulnerabilities to eliminate metastasis.
We focus on therapies that target metabolic programs, cell cycle and anti-cancer immune programs.
We seek to understand the emergent properties of complex collections of tumor cells that self-assemble to cause therapy resistance and metastasis.
We seek to understand new cancer vulnerabilities to eliminate metastasis.
We focus on therapies that target metabolic programs, cell cycle and anti-cancer immune programs.
Latest News
Opportunity: We are recruiting motivated graduate students interested in cancer metastasis, how oncogenes alter metabolism and the cell cycle, and the discovery of new anti-metastatic therapies.
Graduation: September, 2024 - Congratulations, Dr. Ton Montoya, who defended his thesis. Coming soon - his fantastic work describing a new role for alanine metabolism in MYC-driven cancers.
Graduation: June, 2024 - Congratulations, Laurine Idoux, Masters Student from University of Paris, completed studies on oxygen-dependent cancer metabolism and role in metastasis, working closely with and mentored by Daphne Superville.
New Grant: September, 2024 - Excited to start work on a newly funded NIH R01 (MPI) with Dr. Nimmi Ramanujam and her team. Goal is to develop technology for improved spatial analysis of cancer metabolism.
New Grant: September, 2024 - The Goga, Renslo and Kelley groups at UCSF, received an award from the Marcus Precision Cancer Medicine Program to study impact of alanine metabolism in liver and other cancers led by Ton Monyoya. Collaborative studies with Drs. Adam Renslo and Katie Kelly seek to identify new lead compounds and combinatorial approaches to target some of the most devastating human cancers.
New Publication: September, 2024 - Studies led by former post-doc Juliane Winkler, (new Assist. Prof @Univ Vienna) published in J. Clin. Invest. discovered how gene expression programs change during breast cancer metastasis, identifying new mechanisms and possible therapies.
New Publication: June, 2024 - Collaborative studies led by Chris McGinnis (Satpathy lab @Stanford) with Goga Lab members Juliane Winkler and Daphne Superville published in Cancer Cell - explores dynamic changes in immune cells during breast cancer metastasis.
New Publication: February, 2024 - Mauricio Jacobo Jacobo - discovered an important role for an inflamed cell state in chemotherapy resistance in receptor triple-negative breast cancer.
Graduation: September, 2024 - Congratulations, Dr. Ton Montoya, who defended his thesis. Coming soon - his fantastic work describing a new role for alanine metabolism in MYC-driven cancers.
Graduation: June, 2024 - Congratulations, Laurine Idoux, Masters Student from University of Paris, completed studies on oxygen-dependent cancer metabolism and role in metastasis, working closely with and mentored by Daphne Superville.
New Grant: September, 2024 - Excited to start work on a newly funded NIH R01 (MPI) with Dr. Nimmi Ramanujam and her team. Goal is to develop technology for improved spatial analysis of cancer metabolism.
New Grant: September, 2024 - The Goga, Renslo and Kelley groups at UCSF, received an award from the Marcus Precision Cancer Medicine Program to study impact of alanine metabolism in liver and other cancers led by Ton Monyoya. Collaborative studies with Drs. Adam Renslo and Katie Kelly seek to identify new lead compounds and combinatorial approaches to target some of the most devastating human cancers.
New Publication: September, 2024 - Studies led by former post-doc Juliane Winkler, (new Assist. Prof @Univ Vienna) published in J. Clin. Invest. discovered how gene expression programs change during breast cancer metastasis, identifying new mechanisms and possible therapies.
New Publication: June, 2024 - Collaborative studies led by Chris McGinnis (Satpathy lab @Stanford) with Goga Lab members Juliane Winkler and Daphne Superville published in Cancer Cell - explores dynamic changes in immune cells during breast cancer metastasis.
New Publication: February, 2024 - Mauricio Jacobo Jacobo - discovered an important role for an inflamed cell state in chemotherapy resistance in receptor triple-negative breast cancer.